Future Challenges
Overview
These are exciting times for the scientists at the Merck Frosst Centre for Therapeutic Research. Based on our work in asthma and arthritis, we have become world leaders in understanding inflammation and, in particular, the chemistry and biology of leukotrienes and prostaglandins.
Assisted by the very latest technology—gene expression technology, bioinformatics and research information technology—this hard-won legacy of excellence has now generated a new suite of promising research programs, potentially leading to treatments for some of the world's most serious diseases.
A key research area at Merck Frosst is the study of phosphatase enzymes, a class of molecules that represents some of the body's most fundamental control mechanisms. Merck Frosst researchers, in collaboration with researchers from McGill University, have discovered an insulin-receptor phosphatase that could offer an improved target for treatment of disorders such as diabetes and obesity.
Through on-going prostaglandin research we are continuing to build on knowledge gained during the of others medications. Prostaglandins are implicated in pain, inflammation, incontinence, allergic rhinitis and many other conditions.
Other research efforts are focusing on bone disorders, and in particular the systems that control bone remodeling, in the hope that one day such knowledge may lead to better treatments for the devastating bone-thinning disease, osteoporosis.
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