Merck Frosst
Patients and Caregivers

Treatment of asthma can include two categories of MEDICATIONS

  • Controllers (also called preventers) are usually taken on a daily basis to prevent symptoms and asthma exacerbations. They include anti-inflammatory drugs and long-acting bronchodilators (such as long-acting beta2-agonists)
  • Relievers (also called "quick relief medicine") are taken as needed to rapidly relieve acute asthma symptoms. These medications relax the smooth muscles around the airways, thus opening them to help patients to breathe easier.

 


AIRWAYS: UNCONTROLLED ASTHMA


CLEAR AIRWAY—No swelling or narrowing

1
Controllers
Anti-inflammatory drugs
Inhaled corticosteroids Systemic corticosteroids Leukotriene receptor antagonists
PrFlovent® (fluticasone propionate) is a registered trademarks of GlaxoSmithKline.
PrPulmicort® (budesonide) and PrAccolate® (zafirlukast) are registered trademarks of the AstraZeneca Group.
PrQVART (beclomethasone dipropionate) is a trademark of 3M Pharmaceuticals.
PrSINGULAIR® (montelukast sodium) is a Registered Trademark of Merck & Co., Inc. Used under license.

Mode of administration:
inhaled

Mode of administration:
oral or parenteral (such as intravenous)

Mode of administration:
oral

Help to prevent symptoms and exacerbations by reducing inflammation in the airways.

Examples: Flovent®, Pulmicort®, QVAR™

Are usually prescribed for short periods in acute asthma because they are very effective in relieving inflammation and symptoms.

Examples: Prednisone

Help prevent asthma attacks by reducing inflammation in the airways. May be used alone or in addition to other anti-inflammatory drugs. Are not steroids.

Examples: SINGULAIR®, Accolate®

2
Relievers

Long-acting Beta-agonists                             Rapid-acting Beta-agonists
Long-acting inhaled B2-agonists Rapid-acting inhaled B2-agonists
PrBricanyl® (terbutaline sulfate) and PrOxeze® (formoterol fumarate dihydrate) are registered trademarks of the AstraZeneca Group.
PrSerevent® (salmeterol xinafoate) and PrVentolin® ( salbutamol sulfate) are registered trademarks of GlaxoSmithKline.
*Different medications are indicated for different age groups
Mode of administration: inhaled Mode of administration: inhaled

Dilate the airways by relaxing the muscles around them. Are usually used for moderate to severe asthma and their effect lasts for up to 12 hours.

They are bronchodilators, not anti-inflammatories.

Some long-acting inhaled B2-agonists have a slow onset of action (example: Serevent®) and some have a rapid onset of action (example: Oxeze®).

Quickly relieve symptoms by relaxing the muscles of the airways, thus helping to open up the airway and restore normal breathing.

Should only be used as needed. If you have asthma, you should always carry your quick reliever medication with you.

Examples: Bricanyl®, Ventolin®

3
Fixed Dosage Combinations

Fixed dosage combinations
Mode of administration: inhaled
PrAdvair® (salmeterol xinafoate – fluticasone propionate) is a registered trademark of GlaxoSmithKline.
PrSymbicort® (budesonide – formoterol fumarate dihydrate) is a registered trademark of the AstraZeneca Group.
*Different medications are indicated for different age groups

Inhaled corticosteroids are sometimes combined with long-acting inhaled B2-agonists in the same inhaler. These medications are usually prescribed after an initial trial of a single controller agent.

In these cases, the medicine includes a long acting B2-agonist (which dilates your airways) and a corticosteroid (which treats the inflammation).

Examples: Advair®, Symbicort®

PROPER USE of Metered Dose Inhalers (MDIs)

Remove the cap of the inhaler. Then breathe out. Hold the inhaler upright 2-4 cm from your mouth. Breathe in slowly and deeply and immediately depress the canister. Continue to breathe in slowly for 5-10 seconds. Hold your breath for 10 seconds, or as long as it is comfortable. Breathe out slowly. If more than one puff is prescribed, wait 30 seconds and then repeat the procedure.

This site is for residents of Canada. / This site was updated on October 26, 2011.